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KMID : 1143420210140130724
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Public Health Weekly Report
2021 Volume.14 No. 13 p.724 ~ p.733
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COVID-19 Variant Surveillance Study in the Republic of Korea
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Kim Il-Hwan
Park Ae-Kyung
Kim Jeong-Min
Kim Heui-Man
Lee Nam-Joo
Woo Sang-Hee
Lee Chae-Young
Lee Jae-Hee
Rhee Jee-Eun
Kim Eun-Jin
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Abstract
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Recently, the coronavirus disease (COVID-19) virus variants originating in the United Kingdom (UK), South Africa, and Brazil are spreading all over the world, and the variants are known to be different from non-variants in their transmissibility and immune effect. Accordingly, the World Health Organization (WHO) recommended public health measures for variants and proposed working definitions of a variant of concern (VOC) and a variant of interest (VOI).
The Korea Disease Control and Prevention Agency (KDCA) has been continuously monitoring the genotype and the variations of COVID-19 virus through whole genome sequencing analysis from the outbreak of COVID-19 in January 20, 2020, to the present. As a result, 162 VOCs originating from the UK (138), South Africa (18), and Brazil (6) and 61 VOIs originating from California, USA (55), New York, USA (3) and the UK/Nigeria (3). were identified early, and the genome information of the variants confirmed through surveillance were shared in the GISAID DB for international cooperation. To cope with the continuing spread of COVID-19 variants, the KDCA is continuing to strengthen its surveillance system by expanding its analysis capacity. This report was intended to help establish countermeasures to prevent the spread of variants by providing information on the characteristics of variants occurring at domestic and overseas, and the results of domestic surveillance.
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KEYWORD
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Coronavirus disease (COVID-19), Virus variant, Whole genome sequencing analysis
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